| Heart Failure Surgical Trials |
| Acorn MVR |
Evaluation of a heart failure therapy involving surgical implant of a textile mesh wrap, known as the CorCapTM Cardiac Support Device (Acorn CardiovascularTM, St. Paul, MN). The CorCapTM CSD is designed to provide support and relieve stress to the muscle wall associated with advancing heart failure. It is intended to prevent and reverse the progression of heart failure by improving the heart's structure and function, leading to improvements in patient quality of life. www.heartfailureclinicalstudy.com
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| ACORN GEN 2 |
Clinical Evaluation of ACORN CorCap™ Gen 2 Cardiac Support Device which is placed for the treatment of heart failure through a 3-5 inch thoracotomy incision
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| Heart Failure Drug Trials |
| ASCEND-HF |
The evaluation of the FDA approved drug Nesiritide for
patients hospitalized with acute heart failure
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| Stent Trials |
| PLATINUM |
Comparison of the effectiveness and safety of an investigational drug coated stent versus an FDA-approved drug coated stent for coronary artery blockages
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| Hypertension Device Trials |
| RHEOS |
A study of an active implantable device that stimulates the carotid
baroreflex for the treatment of drug resistant hypertension www.bloodpressuretrial.com/
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| Anticoagulation / Anti-Thrombin Drug Trials |
| ARISTOTLE |
A study comparing an investigational blood thinner to warfarin in patients
with an irregular heartbeat
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| TRA 2° P-TIMI 50 |
A study of the thrombin receptor antagonist drug in addition to standard of care treatment in subjects with history of atherosclerotic disease.
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| Hyperlipidemia Drug Trials |
| IMPROVE IT |
Comparison of two different cholesterol lowering regimens for patients that have been hospitalized with a heart attack.
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| SATURN |
Trial to compare the effects of rosuvastatin 40mg with atorvastatin 80mg on the percent atheroma volume of a coronary artery as measured by intravascular ultrasound imaging following 104 weeks of treatment in patients with coronary artery disease
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| Pacer / ICD / Lead Device Trials |
| ELEVATE |
The primary objective of this study is to collect real-time data during pacing testing and characterize performance of an automated device test method
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| SMART AV |
The primary objective of this study is to assess the effect of SmartDelay for determining optimal AV delay timing during CRT compared to both a fixed nominal AV delay and echocardiography-determined optimal AV timing over a 6 month period.
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| CURRENT/PROMOTE |
The primary objective of this study is to evaluate the safety and efficacy of the QuickFlex Model 1258T left heart lead in a patient population indicated for implantable cardioverter defibrillator or cardiac resynchronization therapy. The feature of interest is how much energy is needed and used to regulate the heart.
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